Comparison between Different Modalities

Treatment Modality Comparison Table

Here is the updated table with the HDR Brachytherapy column moved after SBRT:

FactorIMRT (Intensity-Modulated Radiation Therapy)SBRT (Stereotactic Body Radiation Therapy)HDR BrachytherapyProton Therapy
Treatment TechniqueExternal beam therapy with highly modulated radiation beams.External beam therapy with high precision and fewer sessions.Delivers radiation internally via catheters or applicators placed near the tumor.External beam therapy using proton particles.
Radiation DeliveryPhotons (X-rays) directed at tumor from outside the body.High-dose photons in very few treatments.High-dose radiation targeted from inside the body.Protons stop at the tumor, sparing surrounding tissues.
Number of TreatmentsDaily treatments for 5–7 weeks.1–5 treatments over 1–2 weeks.1–5 treatments typically.20–30 treatments for many cancers (fewer for some).
PrecisionHighly precise but some radiation exits through healthy tissues.Extremely precise with tight margins.Very precise, especially for localized tumors.Maximum precision with minimal exit dose.
IndicationsSuitable for many cancers, including prostate, head and neck, and lung.Best for early-stage lung, liver, or other small tumors.Often used for prostate, cervical, and breast cancers.Useful for brain, pediatric, prostate, and complex tumors.
AvailabilityCommonly available in most radiation oncology facilities.Available in many cancer centers, especially large ones.Widely available at specialized cancer centers.Limited to specialized proton therapy centers.
AdvantagesTailored radiation dose to shape of tumor.Short treatment duration with high precision.Direct targeting with minimal collateral damage.Superior tissue sparing and minimal long-term risks.
DisadvantagesLonger treatment course; potential for low-dose radiation exit.Requires precise imaging and planning.Invasive procedure; requires anesthesia for some cases.High cost and limited accessibility.

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